پاسخ : هورمون ریه
در مورد اینکه خود ریه یه هورمون خیلی یونیک و خاص ترشح کنه چیزی نشنیدم . البته شاید سیستم انترواندوکرین اونجا هم یه فعالیت جزیی داشته باشه .
البته هورمون ها روی ریه تاثیر دارن . مثلا متن زیر رو بخونین که از pubmed گرفتم
A number of hormones, including hypothalamic neuropeptides acting as neurotransmitters and neuromodulators in the CNS, are involved in the physiologic regulation of breathing and participate in adjustment of breathing in disease. In addition to central effects, some hormones also control breathing at peripheral chemoreceptors or have local effects on the lungs and airways. Estrogen and progesterone seem to protect from sleep-disordered breathing, whereas testosterone may predispose to it. Progesterone and thyroxine have long been known to stimulate respiration. More recently, several hormones such as corticotropin-releasing hormone and leptin have been suggested to act as respiratory stimulants. Somatostatin, dopamine, and neuropeptide Y have a depressing effect on breathing. Animal models and experimental human studies suggest that also many other hormones may be involved in respiratory control.
در مورد اینکه خود ریه یه هورمون خیلی یونیک و خاص ترشح کنه چیزی نشنیدم . البته شاید سیستم انترواندوکرین اونجا هم یه فعالیت جزیی داشته باشه .
البته هورمون ها روی ریه تاثیر دارن . مثلا متن زیر رو بخونین که از pubmed گرفتم
A number of hormones, including hypothalamic neuropeptides acting as neurotransmitters and neuromodulators in the CNS, are involved in the physiologic regulation of breathing and participate in adjustment of breathing in disease. In addition to central effects, some hormones also control breathing at peripheral chemoreceptors or have local effects on the lungs and airways. Estrogen and progesterone seem to protect from sleep-disordered breathing, whereas testosterone may predispose to it. Progesterone and thyroxine have long been known to stimulate respiration. More recently, several hormones such as corticotropin-releasing hormone and leptin have been suggested to act as respiratory stimulants. Somatostatin, dopamine, and neuropeptide Y have a depressing effect on breathing. Animal models and experimental human studies suggest that also many other hormones may be involved in respiratory control.
پاسخ : هورمون ریه
نه من تو سایت پزشکان بدون مرز خوندم که میگفت :
((بااینکه غدد درون ریز اصلی ترین تولیدکننده های هورمون های بدن هستند، برخی اندام های غیر درون ریز– مثل مغر، قلب، ریه ها، کلیه ها، غده تیموس، پوست و جفت—نیز هورمون تولید کرده و ترشح می کنند.))
[]آشنایی با غده های درون ریز بدن : سایت پزشکان بدون مرز
حالا ریه چی ترشح میکنه ؟؟؟
یه احتمالی هم که وجود داره _به نظر خودم حدس میزنم اینطور باشه_ اینه که این هورمون ناشناخته :24:
از سلول های اپیتلیال آلوئولی نوع II که سورفکتانت هم ترشح میکنند ،ترشح میشه :106:
---- دو نوشته به هم متصل شده است ----
این متن هم میتونه کمک کنه :
[http://link.springer.com/article/10.1007/BF01967969]
نه من تو سایت پزشکان بدون مرز خوندم که میگفت :
((بااینکه غدد درون ریز اصلی ترین تولیدکننده های هورمون های بدن هستند، برخی اندام های غیر درون ریز– مثل مغر، قلب، ریه ها، کلیه ها، غده تیموس، پوست و جفت—نیز هورمون تولید کرده و ترشح می کنند.))
[]آشنایی با غده های درون ریز بدن : سایت پزشکان بدون مرز
حالا ریه چی ترشح میکنه ؟؟؟
یه احتمالی هم که وجود داره _به نظر خودم حدس میزنم اینطور باشه_ اینه که این هورمون ناشناخته :24:
از سلول های اپیتلیال آلوئولی نوع II که سورفکتانت هم ترشح میکنند ،ترشح میشه :106:
---- دو نوشته به هم متصل شده است ----
این متن هم میتونه کمک کنه :
Bombesin, calcitonin and leu-enkephalin immunoreactivity in endocrine cells of human lung
.Bronchial endocrine cells containing gastrin-releasing peptide (GRP), a mammalian analog of bombesin, and adrenocorticotropic hormone (ACTH) were immunohistochemically localized in paraffin sections of normal and pathologic human lungs. GRP-containing cells were present in fetal bronchi at the 12th gestational week and in "neuroepithelial bodies" about the time of delivery. In normal adult lungs, a few isolated GRP-containing cells were present in bronchial and bronchiolar mucosa. In bronchiectatic or fibrotic lungs, small clusters of GRP-containing cells were occasionally noted in basal bronchial mucosa. Pronounced GRP cell hyperplasia often was observed in ectatic bronchioles of lungs with tumorlet. Cells of pulmonary tumorlets mostly showed GRP immunoreactivity. Two bronchial carcinoids exhibited a moderate number of GRP-containing cells. Three of four small cell carcinomas, intermediate cell type could be designated "GRPomas" from the number of GRP-containing cells present. In four of 11 small cell carcinomas, oat cell type, GRP immunoreactivity was infrequently recognized. Immunoabsorption tests indicated that GRP immunoreactivity in lungs would mainly fall under the C-terminal fragment rather than the whole sequence of GRP. Bombesin immunoreactivity in human lungs should be attributed to GRP or GRP-like molecules, since no bombesin immunoreactants were identified with bombesin antiserum which shows no cross-reactivity to porcine GRP. ACTH-containing cells, also reactive to beta-endorphin antiserum, were absent from normal fetal or adult lungs but did accompany GRP-containing cells occasionally in ectatic non-neoplastic bronchioles, always in tumorlet cells, and often in endocrine lung tumors, although the cells containing GRP and ACTH were not identical. The significance of GRP in the physiology and pathophysiology of the lung is discussed, and the necessity of reevaluation of "ectopic" ACTH production in lung neoplasms is proposed
[http://europepmc.org/abstract/med/6188883].Bronchial endocrine cells containing gastrin-releasing peptide (GRP), a mammalian analog of bombesin, and adrenocorticotropic hormone (ACTH) were immunohistochemically localized in paraffin sections of normal and pathologic human lungs. GRP-containing cells were present in fetal bronchi at the 12th gestational week and in "neuroepithelial bodies" about the time of delivery. In normal adult lungs, a few isolated GRP-containing cells were present in bronchial and bronchiolar mucosa. In bronchiectatic or fibrotic lungs, small clusters of GRP-containing cells were occasionally noted in basal bronchial mucosa. Pronounced GRP cell hyperplasia often was observed in ectatic bronchioles of lungs with tumorlet. Cells of pulmonary tumorlets mostly showed GRP immunoreactivity. Two bronchial carcinoids exhibited a moderate number of GRP-containing cells. Three of four small cell carcinomas, intermediate cell type could be designated "GRPomas" from the number of GRP-containing cells present. In four of 11 small cell carcinomas, oat cell type, GRP immunoreactivity was infrequently recognized. Immunoabsorption tests indicated that GRP immunoreactivity in lungs would mainly fall under the C-terminal fragment rather than the whole sequence of GRP. Bombesin immunoreactivity in human lungs should be attributed to GRP or GRP-like molecules, since no bombesin immunoreactants were identified with bombesin antiserum which shows no cross-reactivity to porcine GRP. ACTH-containing cells, also reactive to beta-endorphin antiserum, were absent from normal fetal or adult lungs but did accompany GRP-containing cells occasionally in ectatic non-neoplastic bronchioles, always in tumorlet cells, and often in endocrine lung tumors, although the cells containing GRP and ACTH were not identical. The significance of GRP in the physiology and pathophysiology of the lung is discussed, and the necessity of reevaluation of "ectopic" ACTH production in lung neoplasms is proposed
[http://link.springer.com/article/10.1007/BF01967969]
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